Can Cozaar cause Erectile Dysfunction?
Cozaar (losartan) is a medication that is used to treat various conditions of the heart and blood vessels, including high blood pressure and diabetic nephropathy. It belongs to a class of medications called angiotensin receptor blockers (ARBs) that work by causing the blood vessels to relax which, in turn, allows for easier blood flow and reduced blood pressure. According to the prescribing information for Cozaar, sexual side effects were reported as potential side effects associated with the medication. Erectile dysfunction is a rare side effect of Cozaar, occurring in less than 1 percent of patients taking the medication during clinical studies. Since this side effect was so rare in occurrence it is not entirely clear if the medication is the cause or other factors. If you are experiencing sexual side effects since starting treatment with Cozaar, consult with your healthcare provider for proper evaluation of your symptoms and to determine if treatment is necessary or a change in medication is warranted in your situation.
A drug that has proven successful in treating hypertension, or high blood pressure, may also help improve another condition that plagues older men. Scientists have found that men being treated for hypertension with the drug losartan, who also suffer from sexual dysfunction reported improvement in at least one area of sexuality. The number of men reporting improvement was at 88% during the study. The number of men involved in the study who reported impotence dropped from 75.3 % to 11.8%. The results of this study raise hope for men who have quit taking blood pressure medications because they interfered with sexual function. Sexual dysfunction was defined for the study as decreased libido, impotence and poor sexual satisfaction.
The 12-week study of 164 men, all with hypertension was divided into 2 groups of 82, one group with sexual dysfunction, the other group reported normal sexual functioning. Both groups took losartan in dosages of 50 to 100 milligrams daily for the 12 weeks of the study. In the group of men with sexual dysfunction 88 percent reported improvement in at least one area of sexual function and 73.7% reported an improved quality of life.
The study group of men without sexual dysfunction, the drug did not produce changes in sexual function or satisfaction.
While scientists caution that the results are not definitive, they do point out the need for a larger clinical study. Hypertensive men who are also impotent but who are well controlled on another drug should not be switched to this drug until further study is done.
Carlos Ferrario M.D. states the results of the study also points to the finding that hypertensive drugs do not caused by hypertensive drugs, but is in fact a part of the disease process itself. He feels that the major contributor to impotence in hypotensive men is angiotensin.
Most cases of sexual dysfunction are related to a physical cause. The most common causes are diabetes, heart disease, neurological trauma or disease and side effects of medications. Stress and anxiety can also contribute to impotence. While most of the focus has been on men with erectile dysfunction, a number of women also suffer from this disorder. Exact numbers of suffers are not known as many people do not report these problems to their physicians due to shame. Over the last few years thee have been many exciting advances in the knowledge and treatment of erectile dysfunction, with the most prominent being .
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